%0 Journal Article
%T Effects of Nurse-Led Multidisciplinary Holistic Nonpharmacological Interventions on Fatigue in Hemodialysis Patients: A Randomized Controlled Trial
%A Amol Tanaji Ubale
%A Viswanath Bandi
%A Brintha Jei Jeyaraj
%J Journal of Integrative Nursing and Palliative Care
%@ 3006-5550
%D 2025
%V 6
%N 1
%R 10.51847/nFMS1T6HqO
%P 125-133
%X Fatigue is a common and debilitating symptom among patients undergoing hemodialysis, often causing both mental and physical exhaustion that negatively affects daily functioning, social engagement, and overall quality of life. Despite its impact, the significance of fatigue in this population is often underrecognized, and strategies for its management remain limited. Most prior studies have focused primarily on physical fatigue, with limited consideration of mental fatigue. This study aimed to evaluate the effectiveness of nurse-led, multidisciplinary nonpharmacological integrated care interventions (NICIs) in reducing fatigue among hemodialysis patients. The intervention combined walking exercises, motivational interviewing (MI), and educational sessions on behavioral self-management. A single-center randomized controlled trial was conducted at the dialysis unit of a tertiary university-affiliated hospital from January to June 2019. A total of 118 patients were randomly assigned to the intervention group (IG, n=60) or control group (CG, n=54). Four patients withdrew during the study, leaving 114 participants for analysis. The IG received routine nursing care supplemented with NICIs, while the CG received routine care alone. The intervention lasted six months. Participants in the IG experienced significant improvements compared with the CG, including reductions in overall fatigue (2.26 vs. 0.48), mental fatigue (1.41 vs. 0.54), and muscular fatigue (2.13 vs. 0.75). Additionally, some biochemical parameters, such as serum urea levels, showed significant improvement (P
%U https://journalinpc.com/article/effects-of-nurse-led-multidisciplinary-holistic-nonpharmacological-interventions-on-fatigue-in-hemod-3fgovwpcut4gktg