2022 Volume 3
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Prevalence and Determinants of Severe Pain at the End of Life: A Population-Based Observational Study


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  1. Emergency Department, Maurizio Bufalini Hospital, 47521 Cesena, Italy.
  2. Department of Translational Medicine and for Romagna, University of Ferrara, 44124 Ferrara, Italy.
  3. Pronto Soccorso Ospedale di Imperia, 18100 Imperia, Italy.
Abstract

Managing pain effectively is a cornerstone of quality end-of-life care, yet comprehensive population-level insights into its prevalence and determinants remain scarce. This study examined how often individuals experience significant pain near death and identified factors linked to greater pain burden. Using a retrospective, population-based design, we analyzed all Ontario residents who died between April 1, 2011, and March 31, 2015, and who completed a home care assessment within 30 days before death (n = 20,349). Severe daily pain was determined through linked provincial health databases and measured using a validated composite pain scale that captures both intensity and frequency, defining severe pain as pain of high intensity occurring daily. Severe daily pain was documented in 17.2% of decedents. Higher likelihood of severe pain was associated with being female, younger in age, and having greater functional limitations. Conversely, cognitive impairment was linked to a reduced probability of reporting pain. Patterns varied across disease trajectories—those dying from terminal conditions such as cancer reported more severe pain than individuals with frailty-related deaths (odds ratio = 1.66). While pain is a major concern for many nearing end of life, fewer than 20% experienced severe pain on a daily basis during their final month. Findings highlight the need for proactive, early palliative care engagement—particularly for subgroups at higher risk of distressing pain.


How to cite this article
Vancouver
Prisa D, Cantile T, Dipalma G. Prevalence and Determinants of Severe Pain at the End of Life: A Population-Based Observational Study. J Integr Nurs Palliat Care. 2022;3:61-73. https://doi.org/10.51847/ctbIrqzf19
APA
Prisa, D., Cantile, T., & Dipalma, G. (2022). Prevalence and Determinants of Severe Pain at the End of Life: A Population-Based Observational Study. Journal of Integrative Nursing and Palliative Care, 3, 61-73. https://doi.org/10.51847/ctbIrqzf19
Volume 7 - 2026