Important factors, such as deficits in rumination and emotional processing associated with traumatic events (such as cancer), may influence the maintenance and development of PTSD symptoms. The current study was done to study the effect of memory-specificity training on rumination and emotional processing deficits in cancer patients. This research was a post-test-pre-test type with a control group. 30 cancer patients with symptoms of Post-Traumatic Stress Disorder were selected as samples and randomly replaced in two control and experimental groups. The experimental group underwent 6 sessions of 90 minutes, one day a week for memory specialization training. No intervention was utilized for the control group. After and before the intervention, both groups responded to the emotional processing scale and rumination response scale questionnaires. To analyze the data, the method of covariance multivariate analysis was used using SPSS23 software. Based on the obtained results, there was a remarkable difference between the average post-test scores of the control group and intervention group (P<0.05), so memory specialization training significantly causes the reduction of defects in rumination and emotional processing. A thought intervened in the group. Based on the results of the current study, memory specificity training is a cost-effective and short-term treatment to reduce emotional and cognitive symptoms in cancer patients with Post Traumatic Stress Disorder symptoms, which reduces emotional and cognitive symptoms by increasing memory specificity. Thus, it is recommended as a useful intervention to decrease the emotional and cognitive problems of cancer patients with Post Traumatic Stress Disorder symptoms.