Living liver donors play a crucial role in liver transplantation but face numerous physical and psychological challenges throughout the process. A deeper comprehension of their experiences is essential to deliver holistic, personalized, and patient-centred care. Consequently, this study aimed to collect and integrate existing qualitative research to provide a comprehensive insight into the lived experiences of living liver donors. Following the Enhancing Transparency in Reporting the Synthesis of Qualitative Research guidelines, a meta-synthesis was conducted. Systematic searches of seven databases were conducted from their inception to March 2024, utilizing a combination of Medical Subject Headings and keywords. The data were synthesized using Thomas and Harden’s three-step thematic synthesis technique. A total of nine studies met the inclusion criteria and were included in the synthesis. Analysis revealed four central themes: (1) encountering a life-changing event, (2) navigating shifts in interpersonal relationships, (3) adapting to various changes, and (4) experiencing personal development. Postoperative living liver donors undergo multiple physical, psychological, and social adjustments. Their efforts to manage these challenges highlight the vital role of coping strategies, ultimately leading to personal growth. Future nursing research should prioritize psychological support, interventions, and highlight positive donor experiences to enhance their quality of life.
