Several factors may cause disturbances in the emotional health of nurses and lead to negative coping behaviors (such as the tendency to use drugs). The present study was conducted to investigate the role of mindfulness, dissociative experiences, and feelings of loneliness in predicting the tendency to use drugs in nurses. This study was done by the descriptive-correlation method. Among the statistical population, 220 nurses working in the hospital were selected as available sampling and responded to the mindfulness assessment scale, dissociative experience scale, loneliness questionnaire, and addiction readiness scale. The collected data were analyzed using multiple regression analysis and Pearson's correlation coefficient in SPSS-23 software. The results showed that there is a positive and significant relationship between feelings of loneliness and dissociative experiences with the tendency to use drugs (P<0.01). Based on the results, a negative and significant relationship was reported between mindfulness and the tendency to use drugs (P<0.01). Also, the results of multiple regression analysis revealed that 0.684 variance of active tendency to use drugs and 0.638 variance of passive tendency to use drugs in nurses is explained by mindfulness, dissociative experiences, and loneliness. The results of this research show the significant role of mindfulness, dissociative experiences, and feelings of loneliness in predicting the tendency to use drugs in nurses. Healthcare systems should focus resources on supporting the psychological and emotional health of nurses, and in this regard, special attention should be paid to the role of the components of this study to design effective therapeutic interventions to prevent the tendency to drug use in nurses.
