Long periods of hospitalization will cause problems for the infants and can lead to the weakening of the parent-child relationship and make them feel incompetent. The current study was done to study the impact of music and pre-feeding oral stimulation on the time to gain independent oral feeding in two groups of premature infants. In this clinical trial study, 20 premature infants, girls and boys, with a fetal age of 28-32 weeks, were randomly specified to intervention groups 1 and 2. Intervention group 1 received pre-feeding oral stimulation alone and group 2 received music in addition to that. Based on the results obtained, the use of multiple musical interventions along with oral stimulation accelerates the achievement of independent oral feeding and they achieved independent oral feeding 1.7 days earlier; also, they were discharged on their own almost 1 day earlier than the oral stimulation intervention group. Although this reduction is valuable, in this study no significant effect was observed on the obtained results. Although pre-feeding oral stimulation is effective in reducing the duration of achieving oral feeding, music does not increase this effect.